Displaying episodes 1 - 25 of 25 in total

Ukraine and science, episode 2

How is the Russian invasion of Ukraine affecting scientists? Here is episode 2 on this subject, a conversation with Dr. Svitlana Dekina, a researcher at the A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine in Odessa, Ukraine. She has recently left Ukraine and is now at the European Molecular Biology Laboratory in Heidelberg, Germany. (Art; J. Jackson)

Ukraine and science, episode 1

How is the Russian invasion of Ukraine affecting scientists? Here is a conversation with Dmytro Gospodaryov, a researcher in the department of biochemistry and biotechnology at Vasyl Stefanyk Precarpathian National University in Ivano-Frankivsk, West Ukraine.

Creative grit: the Global South takes on COVID-19, Episode 1

Virologist Dr Marycelin Baba from the University of Maiduguri in northeastern Nigeria has a can-do approach to COVID-19 and other infectious diseases. That is linked to her experience with many viral diseases and her passion for her work.

The CRISPR Children, Episode 4

Around three years ago, three children were born with genomes edited before their birth. They are supposedly doing ok, sources tell me. But it's hard to know for sure. Germline-genome editing is not permissible in most countries, but it might one day be performed to avoid heritable diseases that are incurable. But the technology needs to be much more precise than it is now. In this episode, I speak with Dr. Alison van Eenennaam of the University of California, David about her work in cattle and we also talk about germline-gene editing in people. Note: Some cautions for you. If you don’t like meat, you might not like this podcast. Although you might want to hear about projects related to livestock health and breeding in the tropics or about reviving and restoring endangered species. You might not like this podcast if you do not want to hear about animal experiments. Although we do also know that many things intended for use in people are tested in animals first. And that is indeed fraught. Even if you have aversions of this kind, I would like to invite you to tune in to hear more about Alison van Eenennaam’s work. (Art: J. Jackson)

Predicting protein structure, episode 4

This episode is about AlphaFold and the impact it is having on junior scientists. I spoke with a group of them from different labs at the Max Planck Institute of Biochemistry. (Art: J. Jackson)

Predicting protein structure, episode 3

A chat with conversation with some members of the Rost lab  at the Technical University of Munich. Dr. Maria Littmann, postdoctoral fellow, and PhD students Konstantin Weissenow and Michael Heinzinger and Dr Burkhard Rost, principal investigator.  (Art: J. Jackson)

Predicting protein structure, episode 2

Data about proteins has a home in the Protein Data Bank (PDB). Structural data for over 180,000 proteins. Now, with AlphaFold from DeepMind Technologies, an Alphabet company, there's an EBI-AlphaFold database for structures generated computationally. What does this mean for the Protein Data Bank? And how does the PDB relate to AlphaFold? What's next? Helen Berman, co-founder of the PDB and co-architect of its next chapter shares her thoughts about the future, the past.

Predicting protein structure, episode 1

Protein structure prediction is hard, but AlphaFold, 'an AI' has tackled this big problem. Janet Thornton from the European Bioinformatics Institute and David Jones of University College London look forward, backward and all around on this subject.

The CRISPR Children, Episode 3

To go along with my story The CRISPR Children in Nature Biotechnology, https://www.nature.com/articles/s41587-021-01138-5, I am producing a rolling series of podcasts. This episode is a chat with Dr. Eben Kirksey, an anthropologist at Deakin University. He is the author of the book 'The Mutant Project, Inside the Global Race to Genetically Modify Humans'.  It's dedicated to Lulu and Nana, two of the three children who are known to have had their genomes edited before their birth. 

The CRISPR Children, Episode 2

The CRISPR Children is a series of podcasts about the children whose genomes were edited before their birth. The podcasts accompany a story I did about these children in Nature Biotechnology by the same name. You can find the story here: https://rdcu.be/cB7Nx This episode is based on a conversation with scientist Dr. Rudi Jaenisch of the Whitehead Institute fro Biomedical Research. (Art: J. Jackson)

The CRISPR children, Episode 1

The CRISPR Children is a series of podcasts about the children whose genomes were edited before their birth. The podcasts accompany a story I did about these children in Nature Biotechnology by the same name. You can find the story here: https://rdcu.be/cB7Nx This episode is based on a conversation with physician-scientist Dr. Kiran Musunuru of the University of Pennsylvania. (Art: J. Jackson)

Ask the crab

Neuroscientists use models of the brain to study the brain. One of those model types: organoids. Dr. Eve Marder from Brandeis University talks about what organoids can tell researchers about the brain and what they might be less suited for. And why they are biological theory.

Not lost in space Episode #2

This podcast is about smoothies, fruit salads, fruit tarts and the role of spatial analysis in biology, especially in neuroscience. It's with two scientists from the Allen Institute for Brain Science. Dr. Hongkui Zeng and Dr. Boslijka Tasic.

Not lost in space Episode #1

This podcast is about friendship, stamina, patience and about the role of space in biology. It's about spatially resolved transcriptomics, which is a way to see where things happen in tissues. It's about two Swedish scientists. Dr. Patrik Ståhl and Dr. Fredrik Salmén and their colleagues.

Hello brittlestar

Dr. Paola Oliveri studies marine echinoderms. They have evolved so much novelty, says the developmental biologist from University College London.

Long-COVID Part 3: A chat with Terina Martinez

Long-COVID is rough on many people who have happily recovered from COVID-19. Dr. Terina Martinez, a field application scientist at Taconic Biosciences talks about the challenges of modeling this condition.

Long-COVID Part 1: A chat with Nadia Rosenthal

Long-COVID is tough with its many symptoms for people who have recovered from COVID-19. In this podcast Dr. Nadia Rosenthal, the scientific director of The Jackson Laboratory talks about how more diverse models can help to understand and address long-COVID.

Long-COVID Part 2: A chat with Avi Nath

Long-COVID is hard on many people who have recovered from COVID-19. This is a conversation with Dr. Avi Nath about long-COVID and brain fog. He is intramural clinical director of the National Institute for Neurological Disorders and Stroke (NINDS) at the US National Institutes of Health (NIH).

A chat with with Na Ji

She's driven by curiosity. Na Ji is a physicist and neuroscientist at University of California, Berkeley. She develops ways to study the brain and reads voraciously. (Art: Justin Jackson)

Bye-Bye Bunny

Bye-bye Bunny is about research on COVID-19, about the antibodies in our bodies, and the many kinds of research antibodies. And about the possibility that research antibodies might be generated in animal-free ways instead of involving the use of animals. Episode art: Justin Jackson

Computational pipelines: to build and maintain them

Pipelines are basically a series of data analysis steps rendered computationally. I sat down, virtually that is, with two scientists at DNAnexus to talk about some ways to build and maintain pipelines. Episode art: Justin Jackson

Sneak peak of AACR II 2020

Dr. Elaine Mardis and Dr. Antoni Ribas offer a sneak peek of the AACR annual meeting II and its hundreds of talks and thousands of posters. And they share their thoughts on the pros and cons of virtual conferences. Episode art: Justin Jackson

Job-hunting at ‘ACCR.’

Job-hunting is always hard but job fairs at scientific conferences can be helpful. As the all-virtual virtual annual meeting of the American Association for Cancer Research II gets underway, here are thoughts from job-hunters related to last year’s and this year’s AACR meeting. (Episode art: Justin Jackson)

A chat with Hui Yang

Dr. Hui Yang from the Institute of Neuroscience at Shanghai Institutes for Biological Sciences and his team have developed new base-editors, which are used for gene-editing. It's a long way to clinical applications. This is a story with and about Hui Yang by Vivien Marx. Episode art: Justin Jackson

A chat with Carol Robinson

Dr. Carol Robinson and her team have developed a way to look at small things and big things all in one experiment. The lab is her passion and her joy, says Robinson from the University of Oxford, where she is the first female professor of chemistry. She was previously the first female professor of chemistry at the University of Cambridge. This is a story with and about her by Vivien Marx. Episode art: Justin Jackson